Five STL VentureWorks Innovation Centers Help Grow Businesses From All Industries

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  • Published on May 2, 2017
  • Last Updated June 1, 2021
  • In Coworking

"Each of our incubators has its own personality," says Ginger Imster, VP of Innovation and Entrepreneurship at the St. Louis Economic Development Partnership, the organization that manages the five STL VentureWorks innovation centers. Here is a rundown of each center's features and amenities–and who's there.

STL VentureWorks at Wellston Site Administrator, Vanessa Greene, will celebrate 10 years of service at the Innovation Centers run by the St. Louis Economic Development Partnership (SLEDP) in May.

The five centers located throughout St. Louis City and St. Louis County provide on-site support, connections to capital, networking, customized mentoring and below-market rent to start-up and early-stage small to mid-sized businesses. Businesses graduate from the centers when they’ve grown large enough and profitable enough to be independent.

Greene started at the Grand Center site in 2007, has served at Wellston since 2012, and has seen businesses come into the centers as new startups, then graduate into larger spaces as bigger, successful businesses.

“I’ve watched them come in barely making it and transform into ‘I’ve grown, I’ve graduated, I have my own spot,'” she says. “You see them make it that far–now that’s rewarding.”

“Each of our incubators has its own personality,” says Ginger Imster, VP of Innovation and Entrepreneurship at the St. Louis Economic Development Partnership, the organization that manages the centers.

“We need businesses both large and small to propel our economy forward, and we need both small business owners and tech entrepreneurs to create the dynamism St. Louis must have to attract and retain talent. The STL VentureWorks incubators are an important resource for our local contractors and service professionals excited to build their businesses in St. Louis.”

The five STLVentureWorks innovation centers are spread throughout the region in Grand Center, Creve Coeur, South County, Wellston and West County.

Here’s a rundown of the centers, what they offer and who is growing their companies at each.

Grand Center

Today, STL VentureWorks at Grand Center appeals specifically to food and beverage startups as well as healthcare and general business. Many hospitals, schools and universities are focused on healthcare in and around Grand Center.

The downstairs of Grand Center is a shared commissar, which explains why it is a destination for cooking start-ups. Both Clementine’s Ice Cream and Dog Town Pizza are graduates of STL Venture Works at Grand Center.  Desserts Out the Jar and US International Foods are two current clients at the center.

Office Space: 155-378 square feet
Warehouse/Production Space: 550-2,400 square feet

Helix Center BioTech Incubator
Helix Center BioTech Incubator

Helix Center BioTech Incubator

STLVentureWorks at Helix Center is the newest Innovation Center, having opened in 2012. This center focuses on agricultural technonlogy and plant science, leveraging nearby plant sciences facilities Monsanto and the Danforth Center for Plant Science. The Helix Center is a key element of 39 North, a new AgTech innovation district in the midst of planning and pre-construction activity in Creve Coeur by the SLEDP.

Total space: 33,000 square feet of office and lab space

STLVentureWorks South County

South County

The South County innovation center offers retail space to early stage entrepreneurs and has a distinctly commercial retail design. Current tenant, Isabee’s Beekeeping Equipment and Supplies leverages the center’s retail storefront. Other tenants include KNOWiNK, Travel Unlimited and Century Restoration Co.

Office Spaces: 110 to 1,640 square feet
Warehouse Space: 690 square feet
Retail Space: 1,050 to 1,640 square feet

Wellston STL Venture Works
Rendering of the Wellston STL Venture Works incubation center expansion. | Image courtesy of Atelier3Design.


STLVentureWorks at Wellston is in the midst of an expansion that will double its size. The project is scheduled to be complete before the end of 2017.

This location specializes in light manufacturing and construction trades. In fact, clients at Wellston are contributing to the expansion as architects, concrete manufacturers and flooring specialists. The Wellston Center is close to a MetroLink stop and a Metropolitan Education and Training (MET) facility.

Office: 144 to 320 square feet (may change with expansion)
Warehouse/Production: 496 to 600 square feet (may change with expansion)

St. Louis Venture Works West County

West County

STLVentureWorks at West County is located near the Spirit of St. Louis Airport in Chesterfield Valley. It emerged at a critical time for the valley following the flood of 1993, which decimated the area. Focusing on B2B production, the facility features a variety of products, from promotional items to kits for making Dutch pancakes for resale.

Office Space: 149 to 817 square feet
Warehouses/Production Space: 806 to 1,766 square feet

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