St. Louis Startup Ecosystem Map
The Ultimate List of Startups in St. Louis.
It Takes A City To Raise A Startup
From organizations focused on building tech talent to some of the best accelerator programs in the country, St. Louis’ startup community continues to evolve and grow at a rapid pace.
Why St. Louis?
St. Louis is enjoying a renaissance of entrepreneurship. From a proud heritage of innovation to a thriving startup scene, to available capital, to a supportive ecosystem, the St. Louis region is a place where big ideas can grow.
Upstart City
From household names like Square, Riot Games and Answers.com, to newer ventures like Summersalt, Noonlight and Varsity Tutors, the St. Louis region is exploding with new companies and new ideas. These new companies are innovating in plant and life science, financial services, information technology and advanced manufacturing.
With a rich history of entrepreneurial success, St. Louis has been the launching ground for many of America’s biggest and best companies. Today, a savvy new group of startups is aiming to take their brands global and become drivers of a new St. Louis economy.
With equal parts talent and drive, these entrepreneurs say it’s the environment in St. Louis that helps them succeed quickly. The regional startup ecosystem combines multiple innovation hubs, top-tier entrepreneur support organizations and highly skilled mentors ready and willing to lend advice.
A Thriving Startup Community
There’s a lot of buzz about the innovative culture and entrepreneurial ecosystem in St. Louis. Business incubators provide dense collision points and serve to connect entrepreneurs in new ways. It’s all built on the robust spirit of innovation that is ingrained in the history of St. Louis.
An Incredible Business Ecosystem
St. Louis has a robust ecosystem that enables entrepreneurs to launch and grow their vision. The capital efficiency of the market means founders spend less on real estate and talent, which gives their business longer runways.
An Abundance Of Resources
There’s nothing easy about starting your own company. Which makes the extensive range of private funds and public support in the St. Louis region an asset.
The region has the perfect mix for a growing startup hub: premiere educational institutions, top cultural amenities, strong mentors, competitive cost-of-living and affordable real estate. Plus, venture capital, angel investors, high-profile startup accelerators and public funds are all readily available to startup founders.
Combine that with the region’s innovation districts, which play a leading role in fields such as plant and life science, financial services, information technology, aviation and renewable energy.
Not Just A Startup Renaissance
St. Louis is home to a remarkable number of innovative companies, elite education institutions, and resources designed to nurture and grow big ideas. Meet the founders who relocated their business to St. Louis and make it theirs too.
A Re-invention Of Civic Life
This city is pioneering new approaches to any issue you might want to solve in the 21st century.
The entrepreneurial renaissance that is reshaping the city is the result of the efforts of an unprecedented two-decade-long regional coalition composed of economic development, business, civic, entrepreneurial, political, and venture capital leaders who are united in transforming St. Louis region into a global epicenter of innovation.
There is no better time to start a company, and there’s no better place to start it than in St. Louis.
St Louis Startups
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1 million cups
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100th Monkey
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1904labs
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2b Residential
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39 North
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3D Gloop!
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4 Hands Brewing Company
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4thEst8
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A&C Happy Hour Wine and Spirits
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Accuronix Therapeutics
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Acera Surgical
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Adalo
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Adarza Biosystems
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Advantage Capital Partners
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Advocado
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Aggio
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Aging in Your Place
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AGOGIE
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Agrela Ecosystems
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Aisle411
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Alliance Systems
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Ameren Accelerator
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Amptify
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Anchor
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Answers Corp
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Anvil Analytics + Insights
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API Innovation Center
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Apiary @ The Park
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Appistry
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Applied Particle Technology
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Approach Dating
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Aptimmune Biologics
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Arcade Apartments
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Arch Grants
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Arch Innotek
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Arch Oncology
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Arch Reactor
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Arco + Associates
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Arsenal Capital Management
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Artifox
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Assembly On Demand
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Atomation
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Atomic Revenue
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Atomicdust
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Audubon Associates
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Babyation
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BacterioScan
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BALSA Foundation
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Balto Software
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Bayer Crop Science
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BenchmarkONE
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Benson Hill Biosystems
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Big Heart Tea
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Bigwidesky
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BioGenerator
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BioRankings
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BioSTL
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Blue Line Technology
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Bluestrata EHR
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Bold Spoon Creamery
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Bonfyre
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Books N Bros
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BRDG Park
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Brennan's Work & Leisure
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Brick City Makes
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Buck Surgical
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Butter Love
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Butterscotch Shenanigans
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Cadre Bioscience
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Canopy BioSciences
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Capacity
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Capital Innovators
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CareOrbit
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CareSignal
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CellARide
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Center for Emerging Technologies (CET)
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CentriCrude
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Cervantes Designs
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Cheryl’s Herbs Group
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CIC St. Louis (Cambridge Innovation Center)
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Claim Academy
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Clearent
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Clever Real Estate
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Cofactor Genomics
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Coffeestamp
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Community Development Ventures
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Confluence
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Conflux Co-Learning
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Connect Marketing
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Coolfire Solutions
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Coolfire Studios
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Core + Rind
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CoverCress
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Cultivation Capital
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Customily
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DealMachine
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Decide (formerly LockerDome)
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Deck Commerce
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del Carmen
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DEMIblue
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Denim Social
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Digital Medical Arts
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Dimensions
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Disruptel
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Diverse Business Accelerator
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DIYStyle
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Donald Danforth Plant Science Center
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Dream Builders 4 Equity
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Drug Design Methodologies
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Easytork
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Edison Agrosciences
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EDUrain
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Eemerg Roadside Assistance
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Elasticity
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Equine Smartbits
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Euclises Pharmaceuticals
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Euphrates Vascular
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Exit 11
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Explority
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FastDemocracy
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Filament
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Fimbrion Therapeutics
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FinLocker
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Flipstik
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FocalCast
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Founders Thriving
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Gainsight
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Galera Therapeutics
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Gateway Biotechnology
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Geneoscopy
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Geodata IT
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Geosaurus St. Louis
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GiftAMeal
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Givable
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GlobalHack
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Goal Driven Counseling
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Graphite Lab
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Greater Goods
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Greetabl
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Healthy Bytes
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Healthy Hip Hop
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Helix Center
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Heru Urban Farming
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HIPAAtrek
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Hire Henry
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Hive44
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Homeplan
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HomeTraq
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Honeymoon Chocolates
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HUM Industrial Technology
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Immunophotonics
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Impetus Agriculture
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IncentiLock
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Innovation Hall
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Invisible Industries
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Invisibly
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iSelect Fund
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iSite Media
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ITEN
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Ivani
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Janus Choice
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Jessie B’s Academy
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Journeys Metabolic
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Juristat
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Key2Enable
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KIND soap
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Kingdom Scene Endeavors
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KNOWiNK
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Kwema
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Kypha
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Label Insight
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LeadPost
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Lean Media
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Less Annoying CRM
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Lewis & Clark Ventures
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Lightchain Capital
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Lindenwood University
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Lion Forge
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Lux & Nyx
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MADE
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Made for Freedom
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MagBiosense
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Magnatone
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MakersValley
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MathBRIX
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Medici MediaSpace
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Midwest Digital Marketing Conference (MDMC)
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Mighty Cricket
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Mingo
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Mission Control
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Missouri Technology Corporation (MTC)
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Missouri Venture Forum (MVF)
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Museum of Illusion St. Louis
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Myself Belts
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Nanoguard Technologies
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Nanopore Diagnostics
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National Geospatial-Intelligence Agency (NGA)
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NATIVE AgTech
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Native Pet
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nativeMsg
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Nebula
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Need/Want
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NewLeaf Symbiotics
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NexCore
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Niche Food Group
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NiMONiKS
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NISA Investment Advisors
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Noonlight
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Nvsted
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O'Kelley Building Maintenance
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Obodo
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Observable Networks
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OfCourse Scheduling
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Olio City
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Omniose
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OneSpace
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OPO Startups
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Original Family Smokehouse
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Outside360
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Park Pacific
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PenPath
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Pet Care Innovation Prize
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Phas3
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Pikazo
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Pixel Press
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Plastomics
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Plug
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Pluton Biosciences
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Pointe 400
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Popwallet
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PowerPublish
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Prattle Analytics
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Provider Pool
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Radiologics
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Radius Realty
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Rebundle
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Recursive Labs
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Return To Your Power
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Rezilient
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Riley's Organics
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Riot Games
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RiverVest Venture Partners
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RNAgri
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Rodgers Townsend
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Rooterman
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RoverTown
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Rozzy Learning Company
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Rung for Women
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s4
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Saint Louis Fashion Fund
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Saint Louis Zoo
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SanusEO
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Sapper Consulting
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SaveTheGirls
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Savvy Coders
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Scopio
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SentiAR
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Shine in All Shades
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Sigla
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SixThirty
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SLAM! Agency
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Sling Health
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Sonder Lush Nail Studio
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Soozie's Doozies
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Spark St. Louis
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Sparo
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SpenDebt
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Square One (SQ1)
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Squarefruit Labs
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St. Louis Arch Angels
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St. Louis Economic Development Partnership (SLEDP)
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St. Louis Game Developer Co-op
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St. Louis Public Library
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Stadia Ventures
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Stars Design Group
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Start Right Foods
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SteadyMD
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Stellar Marketing Recruitment
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STL Fusion
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STL Sitter
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Stonemaier Games
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Strange Loop
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Summersalt
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Sunstation
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SwipeSum
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Synchrony Bio
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T-REX
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Tallyfy
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TCARE
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TechArtista
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TechSTL
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TEDx St. Louis
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Tenacity
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The Fattened Caf
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The Leadership Push
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The Yield Lab
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ThriveCo
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Thumbraise
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Tiny Superheroes
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TopOPPS