Cultivation Capital is focused on investing in technology and life sciences companies whose ideas have the potential to transform the way we live and work. With a family of venture funds that invest in technology and life sciences companies, Cultivation helps businesses get to the next level with the help of their investors, general partners and portfolio companies.

Cultivation Capital is a venture capital firm that supports extraordinary entrepreneurs. The firm partners with entrepreneurs who “have the potential to build some of the world’s most successful startups.” The firm actively invests from a variety of funds and supports multiple accelerator programs focusing on areas like financial technology, agriculture technology, and women-led companies.

Currently there are more than 240 investors, 15 general partners, 10 additional accelerator managers, 9 operations team members, 15 analysts, over 36 companies in the portfolio, and over 1200 employees across the portfolio.

For more information, visit Cultivation Capital or follow their updates on:


Cultivation Capital Articles

Twitter Reacts to St. Louis Startup Shame

Decide (LockerDome) Linked to Alt-Right Websites

How to Take TechSTL Beyond Dreams of Single Platform

Clever Raises $8 Million Series B

St. Louis Investors Fund Swiss Geospatial Startup

Balto Raises $37.5M in Series B Funding

Wash U’s Holekamp Seed Fund Awards $1000 to Kickstart 9 Student Ventures

Curate Raises $1.25M Seed Round to Expand SaaS Platform for Creative Businesses

Cultivation Capital to Expand South East to Greenville, South Carolina and Nashville

Maybe St. Louis’s Next Homegrown Unicorn Will Stay Home

Silicon Valley Unicorn Startup Founded in St. Louis Acquired for $1BN

Mission Control Raises $1.75M in Seed Funding

NYC Company Healthy Bytes Raises $1.25M to Relocate to St. Louis

Arch Grants to Provide Equity-Free Funding to 5 Geospatial Startups in 2020

CRM and Email Marketing SaaS Providers, Hatchbuck, Benchmark, Merge

Cultivation Capital Opens Chicago Office

Clever Real Estate Raises $1M From Spirit of St. Louis Fund

The Bourbon Friday Show

The Bourbon Friday Show with Brian Matthews from Cultivation Capital

A “No” from Arch Grants Isn’t a “No” to Your Business

what is venture philanthropy

Venture For America Fellows Are Sticking Around and Crushing It In St. Louis (Just Look at Their Job Titles)

Startup Growth: Slow and Steady — Or Fast and Furious?

Startup Resolutions: Here’s What You’re Chasing In 2018

SafeTrek Closes $3.2 Million Seed Round To Develop Personal Safety App Into A Platform

$5 Million Committed to Fill Valley Of Death Seed Round Funding Void

Cultivation Capital EQ Life Science

Trends in Life Science and Healthcare Innovation

The State of Venture Capital in St. Louis and Promise of New Seed Fund


Givable Aims to Inspire a New Generation of Donors

Meet Bill Schmidt: Managing Partner at Cultivation Capital Life Sciences Fund


Perficient Appoints Brian Matthews to Board of Directors

Chris Danforth

Meet Chris Danforth: General Partner Cultivation Capital Life Sciences Fund

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12 Fundraising Tips for BioTech Companies from Cultivation Capital’s Life Sciences Fund

Founders_Assembly Promise Pay

Assembly Payments Wins eBay Business, Will Power Gumtree Connect

Barry Sandweiss Cultivation Capital

Meet Barry Sandweiss: General Partner at Cultivation Capital

The Yield Lab St. Louis Announces 2017 Portfolio

Adarza BioSystems

Adarza BioSystems Closes on $17 Million – What’s Next for the Life Science Startup

Investments St Louis

The Best Cities in the Midwest for Venture Capital Funding in 2016

St Louis skyline

St. Louis Firms Raise $290 Million of Venture Capital in 2016

BlueStrata Creates 52 New Jobs in Creve Coeur

Peter Esparrago FinLocker

FinLocker and the Digital Mortgage Revolution

Investment Growth STL

2016 Was a Very Big Year for New Venture Funds Launched in St. Louis

Meet Tim Stern: General Partner of Cultivation Capital

T-REX st louis cyber

3 Startup Supporters Share How the T-REX Innovation Center Sets Itself Apart


Cultivation Capital’s Life Sciences Fund Finds Sweet Spot

How to Exit at a Billion: Don’t Think About Exiting

Cultivation Capital Hires New Principal for SixThirty CYBER

Nestlé Purina PetCare & Investment Partners to Award Pet Care Innovation Prize

Cultivation Capital Tech Fund I and Tech Fund II: Investment Update

Cultivation Capital Leads $1.2M Financing Round in S4

Cliff Holekamp: Startup Founder, Educator, Connector, Evangelist

SafeTrek Provides Personal Safety at the Touch of a Button

CB Insights Cultivation Capital Missouri VC

Cultivation Capital Named The Most Active Tech Venture Capital Firm In Missouri By CBInsights

Arch Grants Keeps Its Entrepreneurs in the Ecosystem

STL Startup Funding

STL Startup Funding Guide

Brian Matthews

Capital Ideas: Brian Matthews of Cultivation Capital

Cultivation Capital EQ Life Science

Life Sciences in St. Louis: Q/A with Rick Ryan, General Partner of Cultivation Capital

That’s Life (Sciences)

Label Insight

Label Insight Uses Data To Tell The Real Story Behind Your Food

2015 St. Louis Capital Report: Brian Matthews Outlines Funding From Angels and Venture Capitalists

Cultivation Capital Creates a New Fund to Focus on FinTech Startups

Downtown STL Innovation District Brian Matthews

Downtown St. Louis Innovation Community: 2015 Highlights, 2016 Predictions

St. Charles County Ranks Best in the State for Tech Job Growth

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Founder Series: What Drives Serial Entrepreneur Bob Lozano?


Company Culture: How Hatchbuck’s Team-Driven Approach Drives Results For Everyone

4 Ways To Start Your Career In Startups

Promise Pay SixThirty

PromisePay Aims To Join STL On Rise To Becoming Fintech Hub


How the Startup Ecosystem in Downtown St. Louis is Growing into an Innovation District

5 Locals Nominated to Most Innovative List, TrackBill Raises $1M, Gremlin Social $500K

Why I’m Moving From San Francisco to St. Louis

Olin Cup finalist SynerZ Medical Raises $1M, TrackBill Raises $500K too

Two St. Louis Venture Capital Firms Make Forbes ‘Big Money Midwest’ List

Jim McKelvey Launches New FinTech Accelerator SixThirty