The St. Louis Regional Chamber is proud to announce that as of January 1, 2021, our legacy of engaging and supporting the St. Louis region business community will be carried forward by the newly formed Greater St. Louis, Inc.

Championing a bold vision, Greater St. Louis, Inc. brings together business and civic leaders to create jobs, expand equity and improve St. Louis’ global competitiveness.

The St. Louis Regional Chamber is grateful to its investors and members throughout the years and their steadfast commitment to civic leadership.

The St. Louis Regional Chamber’s core mission is regional economic development – bringing new jobs and companies to the St. Louis metropolitan area, helping existing companies of all sizes grow, encouraging talent and workforce development, and marketing the St. Louis region across the country and the world.

As part of this work, we encourage and collaborate with community partners to encourage entrepreneurship and innovation, support a diverse and inclusive economy, and foster educational opportunities and talent attraction. We are also the region’s principal business advocacy organization, championing forward-thinking economic policies in Illinois, Missouri and Washington D.C.

The Chamber is the region’s largest private-sector business organization and represents the St. Louis business community in both Missouri and Illinois across 15 counties including the City of St. Louis. We want people to know St. Louis is open for business and tell a new story about our region.

For more information, visit Greater St. Louis Inc or follow their updates on:

Greater St. Louis Inc Articles

St. Louis Manufacturing: Tradition and New Direction

St. Louis Business Diversity Initiative Fellows Experience Accepting Applications

Diverse Business Accelerator Offers $5k Equity-Free Funding

TierPoint to Build Fourth Datacenter in Missouri

On Greater STL: Nerdy Diva Owner Touts Benefits of STL Startup Ecosystem

Diverse Business Accelerator Awarded Ewing Marion Kauffman Heartland Challenge Grant

Former Globalhack Executive Director Accepts New Role As Director of Innovation and Entrepreneurship at St. Louis Regional Chamber

The Bourbon Friday Show

The Bourbon Friday Show with Lakesha Mathis from the St. Louis Regional Chamber

St. Louis Regional Chamber Launches Diverse Business Accelerator

Tech Workforce Development in the Region Approaching Crisis Level

3 lessons your city can learn from the St. Louis startup boom

St. Louis Venture Capital Investment Report Spotlights Overall Success but Warns of Critical Inflection Point


St. Louis’ Growing Cybersecurity Community is a Force to be Reckoned With

Andrew Smith

Andrew Smith On Role of Regional Chamber to Bridge the “Valley of Death”

$5 Million Committed to Fill Valley Of Death Seed Round Funding Void


#CEO2CEO: Blake Marggraff of Epharmix and Anthony Tersigni of Ascension on Healthcare Technology

St. Louis Business Leaders Announce Partnership with India, Bring T-Hub to St. Louis

CEO2CEO 2017

CEO2CEO Returns with Blake Marggraff of Epharmix and Anthony Tersigni of Ascension

Andrew Smith

St. Louis Regional Chamber Names Andrew Smith as New VP of Entrepreneurship and Innovation

St. Louis Regional Chamber Awards Arcus Awards to St. Louis Innovators

Arcus Awards

Finalists Announced for 4th Annual St. Louis Regional Chamber Arcus Awards

Accelerate St. Louis Awards $120,000 in Prizes at Startup Connection 2016

St. Louis Startup Roadshow to Boston

7 Startups Share Takeaways STL Startup Roadshow to Boston

Christina Hawatmeh, CEO and Founder of Scopio Startup Roadshow

The First Startup Roadshow Back from New York

Show U St. Louis Festival Set for This Saturday

When St. Louis Innovators Go To Ireland and France: What Happened and What’s Next

15 FinTech Startups Chosen for the St. Louis Startup Roadshow in New York City

Creating an Inclusive Ecosystem: Jason Hall of St. Louis Regional Chamber

Atul Kamra, Managing Partner of SixThirty

SixThirty and St. Louis Recognized as Pioneering FinTech Community

Third Annual Arcus Awards Honor Area Leaders, Companies

St Louis Innovation District

Feature: A Tale of Two Districts

Stadia Ventures Founders Tim Hayden (left) and Art Chou (right)

Stadia Ventures Announces Its First Accelerator Cohort Of Sports Startups


UMB To Partner With Accelerator SixThirty To Kickstart FinTech Startups

Upstart City: Why The Sky Is The Limit When It Comes To St. Louis’ Startup Scene

7 Ways The St. Louis Regional Chamber Is Continuing The Spirit Of St. Louis

T-Rex Purchases Lammert Building With Expansion In Mind

Jim McKelvey Launches New FinTech Accelerator SixThirty