Founded in 2002 through a collaboration of Washington University in St. Louis, BJC Healthcare, the University of Missouri-St. Louis, Saint Louis University, and the Missouri Botanical Garden, the Cortex Innovation Community is a nationally and internationally recognized hub of innovation and technology commercialization. It serves as an anchor in St. Louis’ growing ecosystem of innovative startups and established companies.

Cited by the Brookings Institution as a Best Practice among global urban innovation districts, Cortex is home to 380 technology-related businesses and organizations, and it provides a deep pool of entrepreneurial support programs available to the entire St. Louis community. It is committed to growing urban technology jobs, generating new taxes for the City of St. Louis, and creating an inclusive innovation community.

For more information, visit CORTEX or follow their updates on:

CORTEX Articles

Dream Builders 4 Equity Founder Shares Advice for Aspiring Entrepreneurs

Cortex Partners with Defense Department

Random Thoughts On Why You Should Join Us at STL Startup Week

Register Now for STL Startup Week 9th-13th November: Online Festival & Virtual Conference

General Assembly Opens in St. Louis

Cortex to Hire Vice President of Equity and Inclusion

How Dennis Lower Built Cortex Into Model Innovation District

Finalists for Cortex Garage Artwork to Present Initial Concepts Tomorrow at Venture Cafe

Square's St. Louis office

Square Is Moving Out of Cortex and Into St. Louis Post-Dispatch Building

Cortex Expands with Re-invention of Historic 4340 Duncan Building

The Coworking Guide to St. Louis

Tech Workforce Development in the Region Approaching Crisis Level

Innovation and the Socio-Economic Benefits of a Connected Green City

Boomerang Generation: “The New Magnetism of Mid-Size Cities”

Cortex Metrolink Grand Opening

Cortex Innovation Community Celebrate Aloft Hotel Groundbreaking

T-Rex and Cortex’s Dennis Lower Honored At 2018’s What’s Right With The Region Awards

$50 Million Investment in St Louis from Microsoft Follows Opening of New Building at Cortex

Innovation Hall is Emblematic Of All Our Achievements In Building The St. Louis Startup Ecosystem

St Louis Startup Boom Was 20 Years In The Making

On The Economist: “Millennials Really Like St. Louis”


11 SLU Alumni Who Are Impacting St. Louis’ Tech Scene

Microsoft Announces Move to Cortex Innovation Community

Cortex 3.0

Cortex Looks Ahead: Cortex Special Feature, Chapter 4, 2017 and Beyond

Dennis Lower Cortex Headshot

Cortex Shifts Focus: Cortex Special Feature, Chapter 3, 2010-2016

The groundbreaking of Cortex 1

The Creation of Cortex: Cortex Special Feature, Chapter 2, 2002-2009


Conceiving CORTEX (Early years 2000-2002): Building a New Innovation District in St. Louis

Cortex Innovation Community

Cortex’s Evolution from a Life Science District to a Magnet for St. Louis Innovators: A Feature Series

Tim Hayden and Art Chou of Stadia Ventures

Stadia Ventures Announces Move into Cortex Innovation District

7 Reasons to Get Excited for Murmuration Festival

New Restaurant Vicia To Open in Cortex Innovation District This Fall

Founder Series: Vijoy Rao of Magic Room

How Swizzle’s Founder Left—and Came Back to—St. Louis

Israeli Company NRGene Chooses St. Louis for U.S. Headquarters

What You Need to Know About Cortex Commons This Season

Square Hosts Grand Opening of New Office in Cortex

Global VR/AR Association Launches in St. Louis

Cortex CEO and LouFest Founder Join Forces, Create Festival to Celebrate Intersection of Art, Tech and Music

Maritz & Capital Innovators Partner; Co-Lease Space at Cortex

This Startup is Using Indoor Mapping to Make Shopping Easier

A Year in Review: Cortex’s 6 Biggest Moments of 2015

What’s New with TechShop St. Louis

Gateway Media Acquires Viral Media Site

Phyllis Ellison

What’s Next For St. Louis With Phyllis Ellison

St Louis Innovation District

Feature: A Tale of Two Districts

Cortex St. Louis

Cortex Announces Facilities Partnership with Wash U and SLU

What It Means To Build An Innovation District

Upstart City: Why The Sky Is The Limit When It Comes To St. Louis’ Startup Scene

Startup Scene: Cortex Leading The Way For Innovation Districts

Cambridge Innovation Center’s First Expansion Outside of Massachusetts Opens in St. Louis’ Cortex

How Do You Build An Innovation District?

AB Mauri North America to Move into Cortex