St. Louis Startup Ecosystem Map
The Ultimate List of Startups in St. Louis.
It Takes A City To Raise A Startup
From organizations focused on building tech talent to some of the best accelerator programs in the country, St. Louisโ startup community continues to evolve and grow at a rapid pace.
Why St. Louis?
St. Louis is enjoying a renaissance of entrepreneurship. From a proud heritage of innovation to a thriving startup scene, to available capital, to a supportive ecosystem, the St. Louis region is a place where big ideas can grow.
Upstart City
From household names like Square, Riot Games and Answers.com, to newer ventures like Summersalt, Noonlight and Varsity Tutors, the St. Louis region is exploding with new companies and new ideas. These new companies are innovating in plant and life science, financial services, information technology and advanced manufacturing.
With a rich history of entrepreneurial success, St. Louis has been the launching ground for many of Americaโs biggest and best companies. Today, a savvy new group of startups is aiming to take their brands global and become drivers of a new St. Louis economy.
With equal parts talent and drive, these entrepreneurs say itโs the environment in St. Louis that helps them succeed quickly. The regional startup ecosystem combines multiple innovation hubs, top-tier entrepreneur support organizations and highly skilled mentors ready and willing to lend advice.
A Thriving Startup Community
Thereโs a lot of buzz about the innovative culture and entrepreneurial ecosystem in St. Louis. Business incubators provide dense collision points and serve to connect entrepreneurs in new ways. Itโs all built on the robust spirit of innovation that is ingrained in the history of St. Louis.
An Incredible Business Ecosystem
St. Louis has a robust ecosystem that enables entrepreneurs to launch and grow their vision. The capital efficiency of the market means founders spend less on real estate and talent, which gives their business longer runways.
An Abundance Of Resources
There’s nothing easy about starting your own company. Which makes the extensive range of private funds and public support in the St. Louis region an asset.
The region has the perfect mix for a growing startup hub: premiere educational institutions, top cultural amenities, strong mentors, competitive cost-of-living and affordable real estate. Plus, venture capital, angel investors, high-profile startup accelerators and public funds are all readily available to startup founders.
Combine that with the regionโs innovation districts, which play a leading role in fields such as plant and life science, financial services, information technology, aviation and renewable energy.
Not Just A Startup Renaissance
St. Louis is home to a remarkable number of innovative companies, elite education institutions, and resources designed to nurture and grow big ideas. Meet the founders who relocated their business to St. Louis and make it theirs too.
A Re-invention Of Civic Life
This city is pioneering new approaches to any issue you might want to solve in the 21st century.
The entrepreneurial renaissance that is reshaping the city is the result of the efforts of an unprecedented two-decade-long regional coalition composed of economic development, business, civic, entrepreneurial, political, and venture capital leaders who are united in transforming St. Louis region into a global epicenter of innovation.
There is no better time to start a company, and thereโs no better place to start it than in St. Louis.
St Louis Startups
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100th Monkey
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1904labs
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39 North
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3D Gloop!
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4 Hands Brewing Company
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A&C Happy Hour Wine and Spirits
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Accuronix Therapeutics
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Acera Surgical
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Adalo
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Adarza Biosystems
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Advantage Capital Partners
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Aggio
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Aging in Your Place
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AGOGIE
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Agrela Ecosystems
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Aisle411
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Alliance Systems
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Ameren Accelerator
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Amptify
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Anchor
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Apiary @ The Park
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Applied Particle Technology
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Aptimmune Biologics
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Arcade Apartments
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Arch Innotek
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Arch Oncology
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Arch Reactor
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Arsenal Capital Management
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Artifox
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Assembly On Demand
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Atomation
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Atomic Revenue
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Atomicdust
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Audubon Associates
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BacterioScan
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BALSA Foundation
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Bayer Crop Science
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BenchmarkONE
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Benson Hill Biosystems
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Big Heart Tea
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Bigwidesky
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Blue Line Technology
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Bluestrata EHR
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Bold Spoon Creamery
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Books N Bros
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BRDG Park
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Brick City Makes
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Buck Surgical
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Butter Love
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Butterscotch Shenanigans
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Cadre Bioscience
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Canopy BioSciences
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Capital Innovators
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CareOrbit
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CareSignal
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CellARide
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Center for Emerging Technologies (CET)
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CentriCrude
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Cervantes Designs
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Cherylโs Herbs Group
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Cofactor Genomics
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Coffeestamp
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Community Development Ventures
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Confluence
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Conflux Co-Learning
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Coolfire Solutions
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Coolfire Studios
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Core + Rind
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CoverCress
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Cultivation Capital
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Customily
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DealMachine
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Deck Commerce
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del Carmen
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DEMIblue
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Denim Social
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Digital Medical Arts
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Dimensions
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Disruptel
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Diverse Business Accelerator
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Donald Danforth Plant Science Center
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Dream Builders 4 Equity
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Drug Design Methodologies
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Easytork
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Edison Agrosciences
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EDUrain
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Eemerg Roadside Assistance
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Equine Smartbits
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Euclises Pharmaceuticals
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Euphrates Vascular
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Exit 11
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Explority
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FastDemocracy
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Filament
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Fimbrion Therapeutics
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Flipstik
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FocalCast
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Galera Therapeutics
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Gateway Biotechnology
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Geneoscopy
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Geodata IT
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Geosaurus St. Louis
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GiftAMeal
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Givable
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Goal Driven Counseling
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Greater Goods
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Greetabl
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Healthy Bytes
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Healthy Hip Hop
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Helix Center
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Heru Urban Farming
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HIPAAtrek
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Hire Henry
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Hive44
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Homeplan
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Honeymoon Chocolates
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HUM Industrial Technology
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Immunophotonics
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Impetus Agriculture
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IncentiLock
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Invisible Industries
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Invisibly
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iSite Media
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ITEN
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Ivani
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Janus Choice
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Jessie Bโs Academy
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Journeys Metabolic
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Key2Enable
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KIND soap
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Kingdom Scene Endeavors
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KNOWiNK
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Kwema
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Kypha
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LeadPost
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Lean Media
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Lewis & Clark Ventures
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Lightchain Capital
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Lindenwood University
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Lion Forge
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Lux & Nyx
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MADE
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Made for Freedom
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MagBiosense
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Magnatone
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MathBRIX
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Mighty Cricket
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Mingo
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Mission Control
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Missouri Technology Corporation (MTC)
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Museum of Illusion St. Louis
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Myself Belts
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Nanoguard Technologies
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Nanopore Diagnostics
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NATIVE AgTech
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Native Pet
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Nebula
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NexCore
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Niche Food Group
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NiMONiKS
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NISA Investment Advisors
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Noonlight
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O'Kelley Building Maintenance
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OfCourse Scheduling
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Olio City
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Omniose
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Original Family Smokehouse
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Outside360
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Park Pacific
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PenPath
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Pet Care Innovation Prize
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Phas3
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Pikazo
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Plastomics
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Plug
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Pluton Biosciences
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Pointe 400
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Popwallet
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Prattle Analytics
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Provider Pool
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Radiologics
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Rebundle
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Recursive Labs
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Riley's Organics
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Riot Games
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RiverVest Venture Partners
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RNAgri
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Rodgers Townsend
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Rooterman
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Rozzy Learning Company
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Rung for Women
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s4
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SanusEO
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Sapper Consulting
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SaveTheGirls
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Savvy Coders
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SentiAR
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Shine in All Shades
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Sigla
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SixThirty
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Sling Health
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Sonder Lush Nail Studio
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Soozie's Doozies
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Spark St. Louis
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Sparo
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SpenDebt
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Square One (SQ1)
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Squarefruit Labs
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St. Louis Arch Angels
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St. Louis Economic Development Partnership (SLEDP)
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St. Louis Game Developer Co-op
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St. Louis Public Library
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Stars Design Group
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Start Right Foods
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SteadyMD
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Stellar Marketing Recruitment
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STL Fusion
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STL Sitter
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Stonemaier Games
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Strange Loop
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Summersalt
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Sunstation
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SwipeSum
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Synchrony Bio
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Tallyfy
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TCARE
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TechSTL
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The Fattened Caf
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The Leadership Push
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The Yield Lab
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ThriveCo
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Thumbraise
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Tiny Superheroes
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Tunedly
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UMSL Accelerate
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Upaya Pharmaceuticals
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V15Able
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Vasselโs
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Viosera
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ViTAL
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VR/AR Association
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Wakava
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Washington University in St. Louis (WUSTL)
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WayLit
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Wellbeing Brewing
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WELLTH Holdings
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WeWork St. Louis
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WIFIPLUG
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World Wide Technology
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Wugen
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XEO Air
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YourBevCo
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Zai
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ZenHammer
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zPods